Fisher's rule for combining several p-values

Compute the negative of the log-sum for a vector of p-values.

Usage

comb_pvals(pv)

Arguments

pv

the vector of p-values to be combined together

Value

the Fisher combination of the p-values. See Details.

Details

According to Fisher's rule, if the p-values are correlated, then this does not follow a simple chi-square mixture under the null.